- Original Article
- Thymopentin Therapy in Atopic Dermatitis
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Geun Woong Noh, Ki Young Lee
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Clin Exp Pediatr. 1998;41(9):1268-1272. Published online September 15, 1998
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Purpose : Atopic dermatitis is a chronic relapsing inflammatory skin disease that results from allergic reaction. Steroid therapy has become a major therapeutic modality for treatment of atopic dermatitis. Several immunomodulatory therapies have been tried for atopic dermatitis. In this study thymopentin therapy was performed and its clinical effects and laboratory results were evaluated.
Methods : Atopic dermatitis with typical clinical... |
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- Decrease of Plasma Th2 Cytokines by Interferon(IFN) -γ Therapy in Atopic Dermatitis
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Geun Woong Noh, Woo Gill Lee, Dong Hee Cho, Ki Young Lee
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Clin Exp Pediatr. 1998;41(8):1128-1134. Published online August 15, 1998
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Purpose : Atopic dermatitis is characterized by reduced IFN-γ production and increased IL-4 production. As a result, IgE production increases in atopic dermatitis. In the previous studies, it was reported that recombinant IFN-γ therapy is effective in treatment of severe atopic dermatitis. In this study, changes of plasma IFN-γ, IL-4, IL-5 and IL-10 concentration by IFN-γ therapy were studied in... |
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- In Vitro Immunization-IV: Antibody Response of Mouse Splenocytes Grown in a Mixture of Conditioned Media, Thymocytes, and Bone Marrow Cells
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Dong Soo Kim, Geun Woong Noh
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Clin Exp Pediatr. 1992;35(7):902-908. Published online July 15, 1992
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We have previously reported several methods of in vitro immunization using different conditioned media, and the highest antibody titer was observed when a mixture of three conditioned media[PHA-stimulated adherent splenocytes conditioned medium (ASM-P), ASM-p-stimulated non-adherent splenocyte conditioned medium (NASM-A), ASM-P-stimulated thymocyte conditioned medium (TM-A)] was used.
In this experiment, thymocytes and/or bone marrow cells was added instead of above conditioned media... |
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